Obesity can be a precursor to heart disease, hypertension, and all-cause of mortalities. Obesity inflammation is a “protective” response to the tissue, but in this case the response is chronic, causing cellular deterioration. Visceral fat, for instance, has a low grade of inflammation that contributes to insulin resistance and atherosclerotic (plaque) build up in the vessels. Obesity changes the concentration of leptin, where leptin regulates energy metabolism.
It further resists insulin due to the free fatty acids that go into the liver, from the chemical releases of the cellular visceral fat. Additionally, our body has an antiatherogenic agent that helps prevent the development of atherosclerotic plaque known as adiponectin. The visceral fat reduces adiponectin concentrations which lessens the protective effect of the agent. Physical activity has beneficial affects by reducing fat mass and maintaining muscle. It helps contribute to higher metabolic balances and responses, and consequently, reduces inflammation.
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